The Preemptive Analgesic Effect of Capsaicin Involves Attenuations of Epidermal Keratinocytes Proliferation and Expression of Pro-Inflammatory Mediators After Plantar Incision in Rats

PURPOSE: Subcutaneous infiltration of capsaicin, which initially activates transient receptor potential vanilloid 1 (TRPV1) receptors, can subsequently desensitize TRPV1-expressing nociceptors and induce analgesia in different pain models. Yet, whether the modulation of keratinocytes may also contri...

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Detalles Bibliográficos
Autores principales: Guo, Ruijuan, Qiu, Huanrong, Li, Huili, Ma, Danxu, Guan, Yun, Wang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871044/
https://www.ncbi.nlm.nih.gov/pubmed/36704542
http://dx.doi.org/10.2147/JPR.S395065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871044/
https://www.ncbi.nlm.nih.gov/pubmed/36704542
http://dx.doi.org/10.2147/JPR.S395065

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