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NEDD8-conjugating enzyme E2s: critical targets for cancer therapy

NEDD8-conjugating enzymes, E2s, include the well-studied ubiquitin-conjugating enzyme E2 M (UBE2M) and the poorly characterized ubiquitin-conjugating enzyme E2 F (UBE2F). UBE2M and UBE2F have distinct and prominent roles in catalyzing the neddylation of Cullin or non-Cullin substrates. These enzymes...

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Detalles Bibliográficos
Autores principales: Zhou, Lisha, Lin, Xiongzhi, Zhu, Jin, Zhang, Luyi, Chen, Siyuan, Yang, Hui, Jia, Lijun, Chen, Baofu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871045/
https://www.ncbi.nlm.nih.gov/pubmed/36690633
http://dx.doi.org/10.1038/s41420-023-01337-w