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NEDD8-conjugating enzyme E2s: critical targets for cancer therapy

NEDD8-conjugating enzymes, E2s, include the well-studied ubiquitin-conjugating enzyme E2 M (UBE2M) and the poorly characterized ubiquitin-conjugating enzyme E2 F (UBE2F). UBE2M and UBE2F have distinct and prominent roles in catalyzing the neddylation of Cullin or non-Cullin substrates. These enzymes...

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Detalles Bibliográficos
Autores principales:	Zhou, Lisha, Lin, Xiongzhi, Zhu, Jin, Zhang, Luyi, Chen, Siyuan, Yang, Hui, Jia, Lijun, Chen, Baofu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871045/ https://www.ncbi.nlm.nih.gov/pubmed/36690633 http://dx.doi.org/10.1038/s41420-023-01337-w

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