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Linear-like polypeptide-based micelle with pH-sensitive detachable PEG to deliver dimeric camptothecin for cancer therapy

Nano drug delivery systems have made significant progress in delivering anticancer drugs camptothecin (CPT). However, many challenges for CPT delivery remain, including low drug loading efficiency, premature drug leakage, and poor cellular internalization. Herein, we report a novel dual-sensitive po...

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Detalles Bibliográficos
Autores principales: Wong, Ka Hong, Guo, Zhaopei, Jiang, Di, Zhou, Xingzhi, Lin, Lizhu, Zhao, Denggao, Chen, Meiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871073/
https://www.ncbi.nlm.nih.gov/pubmed/36711109
http://dx.doi.org/10.1016/j.ajps.2022.100773