N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage

Cellular lipid storage is regulated by the balance of lipogenesis and lipolysis. The rate-limiting triglyceride hydrolase ATGL (desnutrin/PNPLA2) is critical for lipolysis. The control of ATGL transcription, localization, and activation has been intensively studied, while regulation of the protein s...

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Detalles Bibliográficos
Autores principales: Xu, Jiesi, Liu, Zhenglong, Zhang, Jianxin, Chen, Siyu, Wang, Wei, Zhao, Xuefan, Zhen, Mei, Huang, Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2023
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871197/
https://www.ncbi.nlm.nih.gov/pubmed/36346641
http://dx.doi.org/10.2337/db22-0362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871197/
https://www.ncbi.nlm.nih.gov/pubmed/36346641
http://dx.doi.org/10.2337/db22-0362

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