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N-end Rule–Mediated Proteasomal Degradation of ATGL Promotes Lipid Storage

Cellular lipid storage is regulated by the balance of lipogenesis and lipolysis. The rate-limiting triglyceride hydrolase ATGL (desnutrin/PNPLA2) is critical for lipolysis. The control of ATGL transcription, localization, and activation has been intensively studied, while regulation of the protein s...

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Detalles Bibliográficos
Autores principales:	Xu, Jiesi, Liu, Zhenglong, Zhang, Jianxin, Chen, Siyu, Wang, Wei, Zhao, Xuefan, Zhen, Mei, Huang, Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2023
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871197/ https://www.ncbi.nlm.nih.gov/pubmed/36346641 http://dx.doi.org/10.2337/db22-0362

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