Neuregulin-1β increases glucose uptake and promotes GLUT4 translocation in palmitate-treated C2C12 myotubes by activating PI3K/AKT signaling pathway

Insulin resistance (IR) is a feature of type 2 diabetes (T2DM) accompanied by reduced glucose uptake and glucose transporter 4 (GLUT4) translocation by skeletal muscle. Neuregulin-1β (NRG-1β) is essential for myogenesis and the regulation of skeletal muscle metabolism. Neuregulin-1β increases insuli...

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Detalles Bibliográficos
Autores principales: Yu, Meirong, Wu, Shuang, Gong, Chao, Chen, Lianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871240/
https://www.ncbi.nlm.nih.gov/pubmed/36703726
http://dx.doi.org/10.3389/fphar.2022.1066279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871240/
https://www.ncbi.nlm.nih.gov/pubmed/36703726
http://dx.doi.org/10.3389/fphar.2022.1066279

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