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Brief research report: Repurposing pentoxifylline to treat intense acute swimming–Induced delayed-onset muscle soreness in mice: Targeting peripheral and spinal cord nociceptive mechanisms

In this study, we pursue determining the effect of pentoxifylline (Ptx) in delayed-onset muscle soreness (DOMS) triggered by exposing untrained mice to intense acute swimming exercise (120 min), which, to our knowledge, has not been investigated. Ptx treatment (1.5, 4.5, and 13.5 mg/kg; i.p., 30 min...

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Detalles Bibliográficos
Autores principales: Borghi, Sergio M., Zaninelli, Tiago H., Saraiva-Santos, Telma, Bertozzi, Mariana M., Cardoso, Renato D. R., Carvalho, Thacyana T., Ferraz, Camila R., Camilios-Neto, Doumit, Cunha, Fernando Q., Cunha, Thiago M., Pinho-Ribeiro, Felipe A., Casagrande, Rubia, Verri, Waldiceu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871252/
https://www.ncbi.nlm.nih.gov/pubmed/36703752
http://dx.doi.org/10.3389/fphar.2022.950314