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Generating a conformational landscape of ubiquitin chains at atomistic resolution by back-mapping based sampling
Ubiquitin chains are flexible multidomain proteins that have important biological functions in cellular signalling. Computational studies with all-atom molecular dynamics simulations of the conformational spaces of polyubiquitins can be challenging due to the system size and a multitude of long-live...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871295/ https://www.ncbi.nlm.nih.gov/pubmed/36704619 http://dx.doi.org/10.3389/fchem.2022.1087963 |