HNF4α Acts as Upstream Functional Regulator of Intestinal Wnt3 and Paneth Cell Fate

BACKGROUND & AIMS: The intestinal epithelium intrinsically renews itself ex vivo via the proliferation of Lgr5(+) intestinal stem cells, which is sustained by the establishment of an epithelial stem cell niche. Differentiated Paneth cells are the main source of epithelial-derived niche factor su...

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Detalles Bibliográficos
Autores principales: Jones, Christine, Avino, Mariano, Giroux, Véronique, Boudreau, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871320/
https://www.ncbi.nlm.nih.gov/pubmed/36464209
http://dx.doi.org/10.1016/j.jcmgh.2022.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871320/
https://www.ncbi.nlm.nih.gov/pubmed/36464209
http://dx.doi.org/10.1016/j.jcmgh.2022.11.010

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