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HNF4α Acts as Upstream Functional Regulator of Intestinal Wnt3 and Paneth Cell Fate

BACKGROUND & AIMS: The intestinal epithelium intrinsically renews itself ex vivo via the proliferation of Lgr5(+) intestinal stem cells, which is sustained by the establishment of an epithelial stem cell niche. Differentiated Paneth cells are the main source of epithelial-derived niche factor su...

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Detalles Bibliográficos
Autores principales:	Jones, Christine, Avino, Mariano, Giroux, Véronique, Boudreau, Francois
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871320/ https://www.ncbi.nlm.nih.gov/pubmed/36464209 http://dx.doi.org/10.1016/j.jcmgh.2022.11.010

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