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Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries
BACKGROUND & AIMS: Chronic hepatitis delta is the most severe form of chronic viral hepatitis and is associated with faster progression towards cirrhosis, liver decompensation, and hepatocellular carcinoma. Hepatitis delta virus (HDV)’s tight dependency on hepatitis B virus and the host cell mac...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871325/ https://www.ncbi.nlm.nih.gov/pubmed/36704052 http://dx.doi.org/10.1016/j.jhepr.2022.100652 |