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Identification of selective hepatitis delta virus ribozyme inhibitors by high-throughput screening of small molecule libraries

BACKGROUND & AIMS: Chronic hepatitis delta is the most severe form of chronic viral hepatitis and is associated with faster progression towards cirrhosis, liver decompensation, and hepatocellular carcinoma. Hepatitis delta virus (HDV)’s tight dependency on hepatitis B virus and the host cell mac...

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Detalles Bibliográficos
Autores principales:	Tseligka, Eirini D., Conzelmann, Stéphanie, Cambet, Yves, Schaer, Tifany, Negro, Francesco, Clément, Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871325/ https://www.ncbi.nlm.nih.gov/pubmed/36704052 http://dx.doi.org/10.1016/j.jhepr.2022.100652

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