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Hypoxia-sensitive miRNA regulation via CRISPR/dCas9 loaded in hybrid exosomes: A novel strategy to improve embryo implantation and prevent placental insufficiency during pregnancy

Assisted reproductive techniques as a new regenerative medicine approach have significantly contributed to solving infertility problems that affect approximately 15% of couples worldwide. However, the success rate of an in vitro fertilization (IVF) cycle remains only about 20%–30%, and 75% of these...

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Detalles Bibliográficos
Autores principales: Yaghoobi, Alireza, Nazerian, Yasaman, Meymand, Arman Zeinaddini, Ansari, Ali, Nazerian, Amirhossein, Niknejad, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871368/
https://www.ncbi.nlm.nih.gov/pubmed/36704201
http://dx.doi.org/10.3389/fcell.2022.1082657