Long-term benefit of immunotherapy in a patient with squamous lung cancer exhibiting mismatch repair deficient/high microsatellite instability/high tumor mutational burden: A case report and literature review

Genetic mutations that render mismatch repair defective may result in microsatellite instability, which is common in colorectal carcinomas and gastric cancers as well as Lynch syndrome. Mismatch repair deficiency/high microsatellite instability (dMMR/MSI-H) predicts the tumor response to immune chec...

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Detalles Bibliográficos
Autores principales: Li, Na, Wan, Zixuan, Lu, Dongyan, Chen, Ruilian, Ye, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871463/
https://www.ncbi.nlm.nih.gov/pubmed/36703977
http://dx.doi.org/10.3389/fimmu.2022.1088683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871463/
https://www.ncbi.nlm.nih.gov/pubmed/36703977
http://dx.doi.org/10.3389/fimmu.2022.1088683

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