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Long-term benefit of immunotherapy in a patient with squamous lung cancer exhibiting mismatch repair deficient/high microsatellite instability/high tumor mutational burden: A case report and literature review
Genetic mutations that render mismatch repair defective may result in microsatellite instability, which is common in colorectal carcinomas and gastric cancers as well as Lynch syndrome. Mismatch repair deficiency/high microsatellite instability (dMMR/MSI-H) predicts the tumor response to immune chec...
Autores principales: | Li, Na, Wan, Zixuan, Lu, Dongyan, Chen, Ruilian, Ye, Xiaowei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871463/ https://www.ncbi.nlm.nih.gov/pubmed/36703977 http://dx.doi.org/10.3389/fimmu.2022.1088683 |
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