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Mechanisms and therapeutic strategies of immune checkpoint molecules and regulators in type 1 diabetes

BACKGROUND: Considered a significant risk to health and survival, type 1 diabetes (T1D) is a heterogeneous autoimmune disease characterized by hyperglycemia caused by an absolute deficiency of insulin, which is mainly due to the immune-mediated destruction of pancreatic beta cells. SCOPE OF REVIEW:...

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Detalles Bibliográficos
Autores principales: Ding, Jia-Tong, Yang, Kang-Ping, Lin, Kong-Lan, Cao, Yu-Ke, Zou, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871554/
https://www.ncbi.nlm.nih.gov/pubmed/36704045
http://dx.doi.org/10.3389/fendo.2022.1090842