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A novel optical imaging probe for targeted visualization of NLRP3 inflammasomes in a mouse model of age-related macular degeneration

PURPOSE: Wet form of age-related macular degeneration (wet AMD) is a progressive vascular disease that mainly affects older adults and causes severe and irreversible vision loss. A key complication of wet AMD is choroidal neovascularization (CNV), which may be driven in part by NLRP3 inflammasomes t...

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Detalles Bibliográficos
Autores principales: Paguaga, Marcell E., Penn, John S., Uddin, MD Imam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871584/
https://www.ncbi.nlm.nih.gov/pubmed/36703888
http://dx.doi.org/10.3389/fmed.2022.1047791