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Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1

AIMS: Therapeutic options targeting post‐ischaemic cardiac remodelling are sparse. The bioactive sphingolipid sphingosine‐1‐phosphate (S1P) reduces ischaemia/reperfusion injury. However, its impact on post‐ischaemic remodelling independently of its infarct size (IS)‐reducing effect is yet unknown an...

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Detalles Bibliográficos
Autores principales: Polzin, Amin, Dannenberg, Lisa, Benkhoff, Marcel, Barcik, Maike, Keul, Petra, Ayhan, Aysel, Weske, Sarah, Ahlbrecht, Samantha, Trojovsky, Kajetan, Helten, Carolin, Haberkorn, Sebastian, Flögel, Ulrich, Zeus, Tobias, Müller, Tina, Gräler, Markus H., Kelm, Malte, Levkau, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871711/
https://www.ncbi.nlm.nih.gov/pubmed/36217778
http://dx.doi.org/10.1002/ehf2.14176