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Dimorphic glioblastoma with glial and epithelioid phenotypes: Clonal evolution and immune selection

PURPOSE: Epithelioid glioblastoma is an unusual histologic variant of malignant glioma. The present study investigates both the genomic and transcriptomic determinants that may promote the development of this tumor. METHODS: Whole-exome sequencing (WES) and whole-transcriptome sequencing (WTS) were...

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Detalles Bibliográficos
Autores principales: Mondia, Mark Willy L., Kritselis, Michael A., Donahue, John E., Elinzano, Heinrich, Sarangi, Sasmit, Bryant, David, Capelletti, Marzia, Korn, W. Michael, Yu, Esther, Yan, Sherry, Toms, Steven A., Wong, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871816/
https://www.ncbi.nlm.nih.gov/pubmed/36703629
http://dx.doi.org/10.3389/fneur.2022.1017087