Case Report: Whole genome sequencing identifies CCDC88C as a novel JAK2 fusion partner in pediatric T-cell acute lymphoblastic leukemia

In the present report, we applied whole genome sequencing (WGS) to genetically characterize a case of pediatric T-cell acute lymphoblastic leukemia (ALL) refractory to standard therapy. WGS identified a novel JAK2 fusion, with CCDC88C as a partner. CCDC88C encodes a protein part of the Wnt signaling...

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Detalles Bibliográficos
Autores principales: Krstic, Aleksandra, Rezayee, Fatemah, Saft, Leonie, Hammarsjö, Anna, Svenberg, Petter, Barbany, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871838/
https://www.ncbi.nlm.nih.gov/pubmed/36704135
http://dx.doi.org/10.3389/fped.2022.1082986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871838/
https://www.ncbi.nlm.nih.gov/pubmed/36704135
http://dx.doi.org/10.3389/fped.2022.1082986

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