Virtual screening and activity evaluation of human uric acid transporter 1 (hURAT1) inhibitors

Hyperuricemia is a disease caused by disorder of purine metabolism, mainly due to insufficient renal excretion of uric acid. Urate transporter 1 (URAT1) is the most widely studied target of urate transporters, and used for uric acid (UA) reabsorption. This study used the AlphaFold2 algorithm to pred...

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Detalles Bibliográficos
Autores principales: Yang, Yacong, Hu, Yu, Yao, Fengli, Yang, Jinbo, Ge, Leilei, Wang, Peng, Xu, Ximing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871872/
https://www.ncbi.nlm.nih.gov/pubmed/36756549
http://dx.doi.org/10.1039/d2ra07193b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871872/
https://www.ncbi.nlm.nih.gov/pubmed/36756549
http://dx.doi.org/10.1039/d2ra07193b

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