What is the role of lipids in prion conversion and disease?

The molecular cause of transmissible spongiform encephalopathies (TSEs) involves the conversion of the cellular prion protein (PrP(C)) into its pathogenic form, called prion scrapie (PrP(Sc)), which is prone to the formation of amorphous and amyloid aggregates found in TSE patients. Although the mec...

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Detalles Bibliográficos
Autores principales: Alves Conceição, Cyntia, Assis de Lemos, Gabriela, Barros, Caroline Augusto, Vieira, Tuane C. R. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871914/
https://www.ncbi.nlm.nih.gov/pubmed/36704327
http://dx.doi.org/10.3389/fnmol.2022.1032541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871914/
https://www.ncbi.nlm.nih.gov/pubmed/36704327
http://dx.doi.org/10.3389/fnmol.2022.1032541

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