Dendritic spine loss deep in the neocortex and dendrite distortion with diffusion disturbances occur early in experimental pneumococcal meningitis

INTRODUCTION: Streptococcus pneumoniae (pneumococcus) meningitis is a serious disease with substantial lethality and long-term disability in survivors. Loss of synaptic staining in the superficial layers of the neocortex in rodent models and in humans, and pneumolysin (a major pneumococcal toxin)-de...

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Detalles Bibliográficos
Autores principales: Baronti, Dario, Tomov, Nikola, Hupp, Sabrina, Mitchell, Timothy J., Iliev, Asparouh I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871924/
https://www.ncbi.nlm.nih.gov/pubmed/36704002
http://dx.doi.org/10.3389/fnins.2022.912445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871924/
https://www.ncbi.nlm.nih.gov/pubmed/36704002
http://dx.doi.org/10.3389/fnins.2022.912445

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