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RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits

RBM46 is a germ cell-specific RNA-binding protein required for gametogenesis, but the targets and molecular functions of RBM46 remain unknown. Here, we demonstrate that RBM46 binds at specific motifs in the 3ʹUTRs of mRNAs encoding multiple meiotic cohesin subunits and show that RBM46 is required fo...

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Detalles Bibliográficos
Autores principales: Lv, Yue, Lu, Gang, Cai, Yuling, Su, Ruibao, Liang, Liang, Wang, Xin, Mu, Wenyu, He, Xiuqing, Huang, Tao, Ma, Jinlong, Zhao, Yueran, Chen, Zi-Jiang, Xue, Yuanchao, Liu, Hongbin, Chan, Wai-Yee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871953/
https://www.ncbi.nlm.nih.gov/pubmed/36726756
http://dx.doi.org/10.1093/procel/pwac040