Cargando…
RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits
RBM46 is a germ cell-specific RNA-binding protein required for gametogenesis, but the targets and molecular functions of RBM46 remain unknown. Here, we demonstrate that RBM46 binds at specific motifs in the 3ʹUTRs of mRNAs encoding multiple meiotic cohesin subunits and show that RBM46 is required fo...
Autores principales: | Lv, Yue, Lu, Gang, Cai, Yuling, Su, Ruibao, Liang, Liang, Wang, Xin, Mu, Wenyu, He, Xiuqing, Huang, Tao, Ma, Jinlong, Zhao, Yueran, Chen, Zi-Jiang, Xue, Yuanchao, Liu, Hongbin, Chan, Wai-Yee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871953/ https://www.ncbi.nlm.nih.gov/pubmed/36726756 http://dx.doi.org/10.1093/procel/pwac040 |
Ejemplares similares
-
RNA binding protein RBM46 regulates mitotic-to-meiotic transition in spermatogenesis
por: Qian, Baomei, et al.
Publicado: (2022) -
Sequential Loading of Cohesin Subunits during the First Meiotic Prophase of Grasshoppers
por: Valdeolmillos, Ana M, et al.
Publicado: (2007) -
Divergent kleisin subunits of cohesin specify mechanisms to tether and release meiotic chromosomes
por: Severson, Aaron F, et al.
Publicado: (2014) -
Aging Predisposes Oocytes to Meiotic Nondisjunction When the Cohesin Subunit SMC1 Is Reduced
por: Subramanian, Vijayalakshmi V., et al.
Publicado: (2008) -
LRRC46 Accumulates at the Midpiece of Sperm Flagella and Is Essential for Spermiogenesis and Male Fertility in Mouse
por: Yin, Yingying, et al.
Publicado: (2022)