Cargando…

High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors

The global COVID-19 coronavirus pandemic has infected over 109 million people, leading to over 2 million deaths up to date and still lacking of effective drugs for patient treatment. Here, we screened about 1.8 million small molecules against the main protease (M(pro)) and papain like protease (PL(p...

Descripción completa

Detalles Bibliográficos
Autores principales: Zang, Yi, Su, Mingbo, Wang, Qingxing, Cheng, Xi, Zhang, Wenru, Zhao, Yao, Chen, Tong, Jiang, Yingyan, Shen, Qiang, Du, Juan, Tan, Qiuxiang, Wang, Peipei, Gao, Lixin, Jin, Zhenming, Zhang, Mengmeng, Li, Cong, Zhu, Ya, Feng, Bo, Tang, Bixi, Xie, Han, Wang, Ming-Wei, Zheng, Mingyue, Pan, Xiaoyan, Yang, Haitao, Xu, Yechun, Wu, Beili, Zhang, Leike, Rao, Zihe, Yang, Xiuna, Jiang, Hualiang, Xiao, Gengfu, Zhao, Qiang, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871955/
https://www.ncbi.nlm.nih.gov/pubmed/36726755
http://dx.doi.org/10.1093/procel/pwac016