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MIF promotes cell invasion by the LRP1-uPAR interaction in pancreatic cancer cells

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) is characterized by high aggressiveness and a hypoxic tumour microenvironment. Macrophage migration inhibitory factor (MIF) is a hypoxia-related pleiotropic cytokine that plays important roles in cancer. However, its role in PDAC progression has...

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Detalles Bibliográficos
Autores principales: Sun, Huizhi, Cheng, Runfen, Zhang, Danfang, Guo, Yuhong, Li, Fan, Li, Yanlei, Li, Yue, Bai, Xiaoyu, Mo, Jing, Huang, Chongbiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9871987/
https://www.ncbi.nlm.nih.gov/pubmed/36703790
http://dx.doi.org/10.3389/fonc.2022.1028070