Evaluating Translational Efficiency of Noncanonical Amino Acids to Inform the Design of Druglike Peptide Libraries

[Image: see text] Advances in genetic code reprogramming have allowed the site-specific incorporation of noncanonical functionalities into polypeptides and proteins, providing access to wide swaths of chemical space via in vitro translation techniques like mRNA display. Prior efforts have establishe...

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Detalles Bibliográficos
Autores principales: Chan, Alix I, Sawant, Manali S., Burdick, Daniel J., Tom, Jeffrey, Song, Aimin, Cunningham, Christian N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872084/
https://www.ncbi.nlm.nih.gov/pubmed/36607609
http://dx.doi.org/10.1021/acschembio.2c00712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872084/
https://www.ncbi.nlm.nih.gov/pubmed/36607609
http://dx.doi.org/10.1021/acschembio.2c00712

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