Engineering the Biosynthesis of Late-Stage Vinblastine Precursors Precondylocarpine Acetate, Catharanthine, Tabersonine in Nicotiana benthamiana

[Image: see text] Vinblastine is a chemotherapy agent produced by the plant Catharanthus roseus in small quantities. Currently, vinblastine is sourced by isolation or semisynthesis. Nicotiana benthamiana is a plant heterologous host that can be used for reconstitution of biosynthetic pathways as an...

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Detalles Bibliográficos
Autores principales: Grzech, Dagny, Hong, Benke, Caputi, Lorenzo, Sonawane, Prashant D., O’Connor, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872167/
https://www.ncbi.nlm.nih.gov/pubmed/36516122
http://dx.doi.org/10.1021/acssynbio.2c00434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872167/
https://www.ncbi.nlm.nih.gov/pubmed/36516122
http://dx.doi.org/10.1021/acssynbio.2c00434

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