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Investigating the Specificity of the Dehydration and Cyclization Reactions in Engineered Lanthipeptides by Synechococcal SyncM

[Image: see text] ProcM-like enzymes are class II promiscuous lanthipeptide synthetases that are an attractive tool in synthetic biology for producing lanthipeptides with biotechnological or clinically desired properties. SyncM is a recently described modification enzyme from this family used to dev...

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Detalles Bibliográficos
Autores principales: Arias-Orozco, Patricia, Yi, Yunhai, Ruijne, Fleur, Cebrián, Rubén, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872173/
https://www.ncbi.nlm.nih.gov/pubmed/36520855
http://dx.doi.org/10.1021/acssynbio.2c00455