Identification of new small molecules as dual FoxM1 and Hsp70 inhibitors using computational methods

BACKGROUND AND PURPOSE: FoxM1 and Hsp70 proteins are highly expressed in many cancers. Thus, their inhibition serves as Bonafede targets in cancer treatment. EXPERIMENTAL APPROACH: FDI-6, an inhibitor of FoxM1, was selected as a template, and based on its structure, a new library from the ZINC datab...

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Detalles Bibliográficos
Autores principales: Alimardan, Zahra, Abbasi, Maryam, Khodarahmi, Ghadamali, Kashfi, Khosrow, Hasanzadeh, Farshid, Mahmud, Aghaei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872178/
https://www.ncbi.nlm.nih.gov/pubmed/36704430
http://dx.doi.org/10.4103/1735-5362.359431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872178/
https://www.ncbi.nlm.nih.gov/pubmed/36704430
http://dx.doi.org/10.4103/1735-5362.359431

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