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Identification of new small molecules as dual FoxM1 and Hsp70 inhibitors using computational methods
BACKGROUND AND PURPOSE: FoxM1 and Hsp70 proteins are highly expressed in many cancers. Thus, their inhibition serves as Bonafede targets in cancer treatment. EXPERIMENTAL APPROACH: FDI-6, an inhibitor of FoxM1, was selected as a template, and based on its structure, a new library from the ZINC datab...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Wolters Kluwer - Medknow
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872178/ https://www.ncbi.nlm.nih.gov/pubmed/36704430 http://dx.doi.org/10.4103/1735-5362.359431 |