Cargando…

RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells

BACKGROUND: Advanced glycation end product receptor (RAGE) acts as a receptor of pro-inflammatory ligands and is highly expressed in alveolar epithelial cells (AECs). Autophagy in AECs has received much attention recently. However, the roles of autophagy and RAGE in the pathogenesis of acute lung in...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Xi, Dou, Jiaying, Shi, Jingyi, Ren, Yuqian, Wang, Chunxia, Zhang, Yucai, Cui, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872382/
https://www.ncbi.nlm.nih.gov/pubmed/36691012
http://dx.doi.org/10.1186/s12931-023-02332-6