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RAGE inhibition alleviates lipopolysaccharides-induced lung injury via directly suppressing autophagic apoptosis of type II alveolar epithelial cells
BACKGROUND: Advanced glycation end product receptor (RAGE) acts as a receptor of pro-inflammatory ligands and is highly expressed in alveolar epithelial cells (AECs). Autophagy in AECs has received much attention recently. However, the roles of autophagy and RAGE in the pathogenesis of acute lung in...
Autores principales: | Xiong, Xi, Dou, Jiaying, Shi, Jingyi, Ren, Yuqian, Wang, Chunxia, Zhang, Yucai, Cui, Yun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872382/ https://www.ncbi.nlm.nih.gov/pubmed/36691012 http://dx.doi.org/10.1186/s12931-023-02332-6 |
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