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The mechanism underlying redundant functions of the YTHDF proteins

The YTH N(6)-methyladenosine RNA binding proteins (YTHDFs) mediate the functional effects of N(6)-methyladenosine (m(6)A) on RNA. Recently, a report proposed that all YTHDFs work redundantly to facilitate RNA decay, raising questions about the exact functions of individual YTHDFs, especially YTHDF1...

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Detalles Bibliográficos
Autores principales: Zou, Zhongyu, Sepich-Poore, Caraline, Zhou, Xiaoming, Wei, Jiangbo, He, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872407/
https://www.ncbi.nlm.nih.gov/pubmed/36694229
http://dx.doi.org/10.1186/s13059-023-02862-8