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Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2

BACKGROUND: Histone methylation modification plays an irreplaceable role in the wheezing diseases. The aim of this study was to explore whether azithromycin (AZM) attenuates post-inflammatory wheezing through inhibiting hypermethylation of histone H3K27me3 mediated by EZH2. RESULTS: A randomized con...

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Detalles Bibliográficos
Autores principales: Wu, Shuqi, Tian, Xiaochun, Mao, Qian, Peng, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872437/
https://www.ncbi.nlm.nih.gov/pubmed/36691058
http://dx.doi.org/10.1186/s13148-023-01430-y