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Pre-hyperglycemia immune cell trafficking underlies subclinical diabetic cataractogenesis

BACKGROUND: This work elucidates the first cellular and molecular causes of cataractogenesis. Current paradigm presupposes elevated blood glucose as a prerequisite in diabetic cataractogenesis. Novel evidence in our model of diabetic cataract challenges this notion and introduces immune cell migrati...

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Detalles Bibliográficos
Autores principales: Ranaei Pirmardan, Ehsan, Zhang, Yuanlin, Barakat, Aliaa, Naseri, Marzieh, Russmann, Christoph, Hafezi-Moghadam, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872438/
https://www.ncbi.nlm.nih.gov/pubmed/36694206
http://dx.doi.org/10.1186/s12929-023-00895-6