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Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study

INTRODUCTION: Chronic cytomegalovirus (CMV) infection is very frequent in people living with HIV (PLWH). High anti-CMV IgG titres, which may be linked to transient CMV replication, have been associated with earlier mortality, CD8 T-cell expansion, lower CD4/CD8 ratio and increased T-cell senescence....

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Detalles Bibliográficos
Autores principales: Royston, Léna, Isnard, Stéphane, Berini, Carolina A., Bu, Simeng, Lakatos, Peter L., Bessissow, Talat, Chomont, Nicolas, Klein, Marina, Lebouché, Bertrand, de Pokomandy, Alexandra, Kronfli, Nadine, Costiniuk, Cecilia T., Thomas, Rejean, Tremblay, Cécile, Boivin, Guy, Routy, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872486/
https://www.ncbi.nlm.nih.gov/pubmed/36690406
http://dx.doi.org/10.1136/bmjopen-2022-067640