Repurposing Carbamazepine To Treat Gonococcal Infection in Women: Oral Delivery for Control of Epilepsy Generates Therapeutically Effective Levels in Vaginal Secretions

Neisseria gonorrhoeae has developed resistance to all previous antibiotics used for treatment. This highlights a crucial need for novel antimicrobials to treat gonococcal infections. We previously showed that carbamazepine (Cz), one of the most commonly prescribed antiepileptic drugs, can block the...

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Detalles Bibliográficos
Autores principales: Shewell, Lucy K., Day, Christopher J., De Bisscop, Xavier, Edwards, Jennifer L., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872610/
https://www.ncbi.nlm.nih.gov/pubmed/36602335
http://dx.doi.org/10.1128/aac.00968-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872610/
https://www.ncbi.nlm.nih.gov/pubmed/36602335
http://dx.doi.org/10.1128/aac.00968-22

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