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Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19

Adintrevimab is a human immunoglobulin G1 monoclonal antibody engineered to have broad neutralization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and other SARS-like coronaviruses with pandemic potential. In both Syrian golden hamster and rhesus macaque models, prop...

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Detalles Bibliográficos
Autores principales: Zumbrun, Elizabeth E., Kaku, Chengzi I., Dillinger, Lukas, Zak, Samantha E., Kuehne, Ana I., Bakken, Russel R., Koehler, Jeffrey W., Delp, Korey L., Stefan, Christopher P., Kumar, Raina, Kugelman, Jeffrey R., Moreau, Alicia M., Zeng, Xiankun, Dye, John M., Herbert, Andrew S., Narayan, Kristin, Walker, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872613/
https://www.ncbi.nlm.nih.gov/pubmed/36519929
http://dx.doi.org/10.1128/aac.01353-22