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Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19
Adintrevimab is a human immunoglobulin G1 monoclonal antibody engineered to have broad neutralization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and other SARS-like coronaviruses with pandemic potential. In both Syrian golden hamster and rhesus macaque models, prop...
Autores principales: | Zumbrun, Elizabeth E., Kaku, Chengzi I., Dillinger, Lukas, Zak, Samantha E., Kuehne, Ana I., Bakken, Russel R., Koehler, Jeffrey W., Delp, Korey L., Stefan, Christopher P., Kumar, Raina, Kugelman, Jeffrey R., Moreau, Alicia M., Zeng, Xiankun, Dye, John M., Herbert, Andrew S., Narayan, Kristin, Walker, Laura M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872613/ https://www.ncbi.nlm.nih.gov/pubmed/36519929 http://dx.doi.org/10.1128/aac.01353-22 |
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