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Pharmacological Profiling of a Brugia malayi Muscarinic Acetylcholine Receptor as a Putative Antiparasitic Target

The diversification of anthelmintic targets and mechanisms of action will help ensure the sustainable control of nematode infections in response to the growing threat of drug resistance. G protein-coupled receptors (GPCRs) are established drug targets in human medicine but remain unexploited as anth...

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Detalles Bibliográficos
Autores principales: Gallo, Kendra J., Wheeler, Nicolas J., Elmi, Abdifatah M., Airs, Paul M., Zamanian, Mostafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9872666/
https://www.ncbi.nlm.nih.gov/pubmed/36602350
http://dx.doi.org/10.1128/aac.01188-22