Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE(2)-mediated amplification of CCR7-related trafficking of infected inflammatory monocytes

People are infected with Leishmania donovani when the parasite is deposited in the dermis during the blood meal of the sand fly vector. Most infected people develop a subclinical latent infection, but some develop progressive visceral leishmaniasis. Malnutrition is a risk factor for the development...

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Detalles Bibliográficos
Autores principales: Osorio, E. Yaneth, Uscanga-Palomeque, Ashanti, Patterson, Grace T., Cordova, Erika, Travi, Bruno L., Soong, Lynn, Melby, Peter C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873180/
https://www.ncbi.nlm.nih.gov/pubmed/36630476
http://dx.doi.org/10.1371/journal.pntd.0011040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873180/
https://www.ncbi.nlm.nih.gov/pubmed/36630476
http://dx.doi.org/10.1371/journal.pntd.0011040

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