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Malnutrition-related parasite dissemination from the skin in visceral leishmaniasis is driven by PGE(2)-mediated amplification of CCR7-related trafficking of infected inflammatory monocytes
People are infected with Leishmania donovani when the parasite is deposited in the dermis during the blood meal of the sand fly vector. Most infected people develop a subclinical latent infection, but some develop progressive visceral leishmaniasis. Malnutrition is a risk factor for the development...
Autores principales: | Osorio, E. Yaneth, Uscanga-Palomeque, Ashanti, Patterson, Grace T., Cordova, Erika, Travi, Bruno L., Soong, Lynn, Melby, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873180/ https://www.ncbi.nlm.nih.gov/pubmed/36630476 http://dx.doi.org/10.1371/journal.pntd.0011040 |
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