Effects of half-dose spiomet treatment in girls with early puberty and accelerated bone maturation: a multicenter, randomized, placebo-controlled study protocol

BACKGROUND: A “mismatch” sequence of less prenatal weight gain and more postnatal weight gain may lead to ectopic lipid accumulation, and trigger the development of early adrenarche/pubarche and the activation of the gonadotropic axis resulting in early puberty and ending up in full-blown adolescent...

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Detalles Bibliográficos
Autores principales: Bassols, Judit, de Zegher, Francis, Diaz, Marta, Carreras-Badosa, Gemma, Garcia-Beltran, Cristina, Puerto-Carranza, Elsa, Oliver-Vila, Cora, Casano, Paula, Franco, Céline Alicia, Malpique, Rita, López-Bermejo, Abel, Ibáñez, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873221/
https://www.ncbi.nlm.nih.gov/pubmed/36694227
http://dx.doi.org/10.1186/s13063-022-07050-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873221/
https://www.ncbi.nlm.nih.gov/pubmed/36694227
http://dx.doi.org/10.1186/s13063-022-07050-w

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