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Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer’s circuit dysfunction
Neurodegenerative diseases are characterized by selective vulnerability of distinct cell populations; however, the cause for this specificity remains elusive. Here, we show that entorhinal cortex layer 2 (EC2) neurons are unusually vulnerable to prolonged neuronal inactivity compared with neighborin...
Autores principales: | Zhao, Rong, Grunke, Stacy D, Wood, Caleb A, Perez, Gabriella A, Comstock, Melissa, Li, Ming-Hua, Singh, Anand K, Park, Kyung-Won, Jankowsky, Joanna L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873254/ https://www.ncbi.nlm.nih.gov/pubmed/36468693 http://dx.doi.org/10.7554/eLife.83813 |
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