Design, synthesis and evaluation of quinoline-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer’s disease

A series of novel quinoline-O-carbamate derivatives was rationally designed for treating Alzheimer’s disease (AD) by multi-target-directed ligands (MTDLs) strategy. The target compounds were synthesised and evaluated by AChE/BuChE inhibition and anti-inflammatory property. The in vitro activities sh...

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Detalles Bibliográficos
Autores principales: Chen, Hongsong, Mi, Jing, Li, Sen, Liu, Zhengwei, Yang, Jing, Chen, Rui, Wang, Yujie, Ban, Yujuan, Zhou, Yi, Dong, Wu, Sang, Zhipei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873282/
https://www.ncbi.nlm.nih.gov/pubmed/36688444
http://dx.doi.org/10.1080/14756366.2023.2169682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873282/
https://www.ncbi.nlm.nih.gov/pubmed/36688444
http://dx.doi.org/10.1080/14756366.2023.2169682

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