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Genomic Signatures from Clinical Tumor Sequencing in Patients with Breast Cancer Having Germline BRCA1/2 Mutation

PURPOSE: BRCA1 and BRCA2 are among the most important genes involved in DNA repair via homologous recombination (HR). Germline BRCA1/2 (gBRCA1/2)-related cancers have specific characteristics and treatment options but conducting gBRCA1/2 testing and interpreting the genetic imprint are sometimes com...

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Detalles Bibliográficos
Autores principales: Kim, Ju Won, Kang, Hyo Eun, Choi, Jimi, Yun, Seung Gyu, Jung, Seung Pil, Bae, Soo Yeon, You, Ji Young, Choi, Yoon-Ji, Kim, Yeul Hong, Park, Kyong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873314/
https://www.ncbi.nlm.nih.gov/pubmed/35681111
http://dx.doi.org/10.4143/crt.2021.1567