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A Phase II Study of Preoperative Chemoradiotherapy with Capecitabine Plus Simvastatin in Patients with Locally Advanced Rectal Cancer

PURPOSE: The purpose of this phase II trial was to evaluate whether the addition of simvastatin, a synthetic 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, to preoperative chemoradiotherapy (CRT) with capecitabine confers a clinical benefit to patients with locally advanced rectal cancer...

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Detalles Bibliográficos
Autores principales: Jo, Hyunji, Kim, Seung Tae, Lee, Jeeyun, Park, Se Hoon, Park, Joon Oh, Park, Young Suk, Lim, Ho Yeong, Yu, Jeong Il, Park, Hee Chul, Choi, Doo Ho, Park, Yoonah, Cho, Yong Beom, Huh, Jung Wook, Yun, Seong Hyeon, Kim, Hee Cheol, Lee, Woo Yong, Kang, Won Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Cancer Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9873315/
https://www.ncbi.nlm.nih.gov/pubmed/35681110
http://dx.doi.org/10.4143/crt.2021.1527